About Us
ToxPharm is an independent consulting company providing scientific and regulatory toxicology guidance.
Bonnie Coffa, PhD is the founder of ToxPharm LLC. Bonnie is a pharmacologist by training with extensive experience in the consumer goods industry, specifically working in regulatory toxicology and FDA submissions.
EDUCATION
- Doctor of Philosophy (Ph.D.) Pharmacology, Vanderbilt University Medical Center- Nashville, TN
LICENSES & CERTIFICATIONS
- 2018 Data Integrity Training
- 2016 Good Laboratory Practices Training
- 2016 Writing Workshop: Succinct Scientific Writing from Hurley Write
- 2013 National Institutes of Health Introduction to Clinical Research Certificate
PUBLICATIONS
- Coffa BG, Zhang J, McKinney WJ, and Lee KM. Toxicological Evaluation of E-liquid Formulations Using In Vitro Genotoxicity and Cytotoxicity Assays. Manuscript in preparation.
- Thaikoottathil J, Doshi U, Coffa BG, Hurtado S, Wells M, Moore MM and Lee KM. Comparison of in vitro cytotoxicity and genotoxicity of condensates derived from e-vapor products and combustible cigarettes. Manuscript in preparation.
- Coffa BG, Coggins C, Werley MS, Oldham MJ and Fariss MF. Chemical, physical, and in vitro characterization of research cigarettes containing denicotinized tobacco. Regulatory Toxicology and Pharmacology. 2016; 79: 64-73.
- Garcia BG, Neely MD, and Deutch AY. Cortical regulation of striatal medium spiny neuron dendritic remodeling in parkinsonism: modulation of glutamate release reverses dopamine depletion-induced dendritic spine loss. Cerebral Cortex 2010 Oct; 20(10):2423-32.
- Sheffler DJ, Kroeze WK, Garcia BG, Deutch AY, Hufeisen SJ, Leahy P, Bruning JC, Roth BL. p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4717-22.
- Garcia BG, Wei Y, Moron JA, Lin RZ, Javitch JA, Galli A. Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution. Mol Pharmacol. 2005 Jul; 68(1):102-9.